Naturally occurring in mushrooms, Ergothioneine is an antioxidant that isn't naturally produced by the human body—yet our skin cells have a dedicated transporter built to draw it in. 

Clinical research shows Ergothioneine settles into mitochondria, the energy center of a cell, enhancing each skin cell's ability to defend against oxidative damage.

Your skin is faced with the real effects of the sun, pollution, and everyday environmental exposure—and Ergothioneine meets that exposure where it matters most: within the cell, at the source of its energy.  

Mitochondria sustain a cell's function over time, and defending them is why Ergothioneine is known as the longevity antioxidant.

Turkey Tail and Tremella Mushroom, both rich in Ergothioneine, are hero ingredients found in LESSE formulas. The Regeneration Mist, an adaptogenic daily treatment formulated with both mushrooms to restore barrier integrity and rebalance stressed skin, and the Essential Moisturizer, featuring  Tremella, works to restore, fortify, and brighten compromised skin.

Fig 2. 
LESSE Regeneration Mist, rich in Ergothioneine.

LESSE Reading List: Ergothioneine

01 Study of Skin Cells & l-ergothioneine

02 Mushrooms In Skin Care Pt. I 

03 Mushrooms in Skin Care Pt. II