Clinically Proven, Active Botanical Skin Care

Clinically proven, dermatologist-recommended skin care that merges

nature's leading botanicals and advanced biotechnology

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Results-driven formulas to

restore, nourish, and awaken skin.

Merging the best of science and nature for visible, enduring results.

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Skin Analysis

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OUR FOUNDER

LESSE was founded in 2018 by Neada Deters, a skin expert and former beauty editor.

After more than a decade of searching for organic, efficacious solutions to her own skin concerns, she set out to create her own. Results-driven essentials made with nature's most potent plant actives.

READ OUR STORY

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EXPLORE THE COLLECTION

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One of the world's richest natural sources of vitamin C, Acerola delivers potent antioxidant defense while promoting collagen synthesis and improving skin radiance.

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Astaxanthin is shown to be 6,000x stronger than vitamin C. This potent antioxidant defends against photoaging, visibly improves elasticity, and reduces the appearance of fine lines.

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This Australian native botanical is exceptionally rich in antioxidants and bioactives—fortifying skin on a cellular level, promoting collagen integrity, and visibly correcting uneven tone.

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Clinically proven to boost collagen synthesis by up to 77%, accelerating wound healing and improving skin firmness, elasticity, and hydration—while reducing inflammation.

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The world’s richest natural source of vitamin C, Kakadu Plum enhances collagen formation, brightens skin tone, neutralizes oxidative stress, and fortifies the skin barrier like no other.

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Native to Australia, this super berry has potent antioxidant activity and has been shown to inhibit melanogenesis, helping brighten skin and reduce the appearance of sun-induced spots.

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A powerhouse of bioavailable minerals, Irish Sea Moss delivers over 90 trace minerals essential for skin function. High in zinc, it helps reduce inflammation, regulate oil production, and support barrier integrity.

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A natural source of polysaccharides that hold 500x their weight in water—Tremella is clinically shown to be more hydrating than hyaluronic acid, retaining up to 500% more moisture while visibly softening skin.

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Clinically studied for its immune-modulating beta-glucans, Turkey Tail enhances skin resilience, supports hydration, and helps fade and prevent hyperpigmentation through the inhibition of tyrosinase—an enzyme involved in melanin production.

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The gold standard in sun protection, this mineral UV filter that provides broad-spectrum protection while offering anti-inflammatory benefits—ideal for sensitive, acne-prone, or reactive skin types.

` ,"rich_in": ["Non-nano Zinc Oxide"] ,"found_in": ["gid://shopify/Product/8153605112095"] ,"image": "//lesseofficial.com/cdn/shop/files/zinc.jpg?v=1747503892" } }] }

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LESSE JOURNAL

THE IMPORTANCE OF BIOAVAILABILITY IN SKIN CARE

The efficacy of your skin care is determined by both the concentration of active ingredients, and their bioavailability.